INSTITUT DE RECHERCHE AGRICOLE POUR LE DEVELOPPEMENT
Un outil privilégié pour le développement agricole et rural du Cameroun

COBE Project

Can onchocerciasis be eliminated? Epidemiological, entomological and parasitological studies in a bovine model in Cameroon.

The research Questions of the present project are:

Is the ongoing transmission still high enough to maintain endemicity?

How does the parasite regulate its population density in both the vector and vertebrate host and how is the adult worm and microfilarial turnover governed in the bovine host?

How big is the risk that emerging ivermectin resistance may spread?

Is there any gene-flow between O. ochengi and O. volvulus or other local Onchocerca species and strains.

How many of the adult worms present in a host do contribute to the population of circulating microfilariae?


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